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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
33.33
Human Site:
T587
Identified Species:
56.41
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
T587
R
R
W
V
L
T
G
T
P
I
Q
N
S
L
K
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
T587
R
R
W
V
L
T
G
T
P
I
Q
N
S
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
T684
R
R
W
V
L
T
G
T
P
I
Q
N
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
T581
R
R
W
V
L
T
G
T
P
I
Q
N
S
L
K
Rat
Rattus norvegicus
NP_001099948
974
110023
T552
R
R
W
V
L
T
G
T
P
I
Q
N
S
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
P535
G
K
P
V
L
E
L
P
E
R
K
V
F
I
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
T577
R
R
W
I
L
T
G
T
P
I
Q
N
S
L
K
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
P561
W
S
R
I
I
Q
R
P
V
T
M
G
D
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
T633
Y
R
W
A
L
T
G
T
P
I
Q
N
K
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
T664
C
K
W
A
L
T
G
T
P
I
Q
N
S
I
K
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
V450
R
R
T
K
D
K
G
V
V
G
L
P
S
K
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
G532
T
K
E
K
S
L
I
G
L
P
P
K
T
V
E
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
I441
I
Q
T
L
L
K
N
I
M
L
R
R
T
K
V
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
T759
H
R
W
V
L
T
G
T
P
I
V
N
R
L
E
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
N.A.
93.3
0
N.A.
66.6
N.A.
N.A.
73.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
40
N.A.
100
13.3
N.A.
66.6
N.A.
N.A.
86.6
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
26.6
N.A.
N.A.
0
6.6
73.3
P-Site Similarity:
26.6
N.A.
N.A.
26.6
40
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
8
0
0
8
0
0
8
0
0
0
0
8
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
72
8
0
8
0
8
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
15
8
0
8
8
0
65
0
0
0
15
0
% I
% Lys:
0
22
0
15
0
15
0
0
0
0
8
8
8
15
50
% K
% Leu:
0
0
0
8
79
8
8
0
8
8
8
0
0
50
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
65
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
15
65
8
8
8
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
58
0
0
0
8
% Q
% Arg:
50
65
8
0
0
0
8
0
0
8
8
8
8
8
0
% R
% Ser:
0
8
0
0
8
0
0
0
0
0
0
0
58
0
0
% S
% Thr:
8
0
15
0
0
65
0
65
0
8
0
0
15
0
8
% T
% Val:
0
0
0
50
0
0
0
8
15
0
8
8
0
8
15
% V
% Trp:
8
0
65
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _